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To propose a new health condition that is not already considered by the UK NSC, please follow this link.
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The UK NSC recommendation on Severe Combined Immunodeficiency (currently under review)


This recommendation is currently being reviewed as part of the UK NSC's regular review cycle of all policies.

The review process began in Dec 2015 and is estimated to be completed by Dec 2017.

Recommendation Systematic population screening programme not recommended
Key downloads

Find general information about population health screening.

More about SCID

Severe combined immunodeficiency (SCID) is a group of genetic disorders characterised by the absence of humoral and cellular immunity. Left untreated in childhood, it can be fatal due to the severe vulnerability to common and opportunistic infections.

The most common treatment for SCID is haematopoietic stem cell transplant (HSCT) derived from bone marrow donors.


Ataxia Telangiectasia Society
British Association of Perinatal Medicine
British Paediatric Allergy, Immunology and Infection Group
British Society for Immunology
CGD Society
Children Living with Inherited Metabolic Diseases
Faculty of Public Health
Genetic Alliance UK
INGID - International Nursing Group for Immunodeficiencies
IPOPI - International Patient Organisation for Primary Immunodeficiencies
Primary Immunodeficiency UK
Royal College of General Practitioners
Royal College of Paediatrics and Child Health
Royal College of Physicians
Royal College of Physicians and Surgeons of Glasgow
Royal College of Physicians of Edinburgh
Save Babies Through Screening Foundation UK
UK Primary Immune-deficiency Patient Support
UK Primary Immunodeficiency Network

The stakeholder groups will be involved when the recommendation is next reviewed. If you think your organisation should be added, please contact us. More information for stakeholders can be found in appendix C of the UK NSC evidence review process.

Related documents

icon One page summary of SCID recommendation (June 2017) (PDF document, 70KB, 04/08/17)
icon UK NSC recommendation summary (June 2017) (PDF document, 227KB, 04/08/17)

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