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Current UK NSC recommendations > Sickle Cell Disease (newborn)

The UK NSC recommendation on Sickle cell disease screening in newborns (currently under review)

 

This recommendation is currently being reviewed as part of the UK NSC's regular review cycle of all policies.

The review process began in Mar 2015 and is estimated to be completed by Feb 2017.

Recommendation Systematic population screening programme recommended
 
Key downloads
 

Evidence to support continuation or cessation of existing screening programmes should be reviewed regularly. The process for this is currently being revised, which is why this topic does not currently have a review date. The new process will be published in due course. Each programme has an active portfolio of research, evidence and audit to support continual improvement. Find out more about sickle cell disease screening, as part of the newborn blood spot screening programme in England.

 

Find general information about population health screening.

More about Sickle Cell Disease (newborn)

Sickle Cell disorders are a group of inheritable genetic conditions in which there is an abnormality of the haemoglobin. Haemoglobin carries oxygen to the various organs of the body and is contained in the red blood cells. In the sickle cell disorders some of the red blood cells assume a sickle shape following the release of oxygen. This abnormal shape causes the cells to clump together making their passage through smaller blood vessels difficult, which may lead to blockage of these small blood vessels and an associated inflammatory reaction.

» Read more about sickle cell and thalassaemia on NHS Choices

Screening in the UK

Compare how screening is offered across the UK.

Stakeholders

Genetic Alliance UK
Royal College of General Practitioners
Royal College of Midwives
Royal College of Paediatrics and Child Health
Sickle Cell Care Centre
Sickle Cell Society

The stakeholder groups will be involved when the recommendation is next reviewed. If you think your organisation should be added, please contact us. More information for stakeholders can be found in appendix C of the UK NSC evidence review process.

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